Know how

The IMPACT core facility offers a complete range of technologies :

• Analysis of protein expression profiling in cells, protein phosphorylation and signaling profiling using dedicated protein chips (protein microarray, SPRimaging) and multiparametric technologies (label free, alpha screen)
• Characterization of molecular interactions using analytical technologies (SPR, microcalorimetry, interferometry)
• Screening of protein or chemical modulators using high-throughput screening technologies and validated target libraries (HTRF, BRET, ALPHA screen)
• Integration of data from profiling or screening technologies using bioinformatics tools (Galaxy interface)

Applications

• Thermodynamics, interaction kinetics
• Diagnostics for medicine and human health
• Biochemistry and biophysics
• Enzymology, protein chemistry, in vitro experiments